Denosyl is a premium liver support supplement for dogs and cats, formulated withS-Adenosylmethionine (SAMe) to promote optimal liver function and cognitive health. This supplement enhances liver detoxification by boosting glutathione levels, a key antioxidant essential for liver cell protection. Additionally, it may support brain function in aging dogs, acting as a neuroprotector to aid cognitive health.
Denosyl tablets feature an enteric coating to improve bioavailability, ensuring that SAMe reaches your pets system effectively. Backed by Nutramax Laboratories Veterinary Sciences, the #1 veterinarian-recommended supplement company, Denosyl is a trusted choice for liver support in pets.
Liver Detoxification & Protection
Cognitive Support for Aging Dogs
Scientifically Proven Bioavailability
Veterinarian-Recommended Formula
Easy Administration
For best results, administer Denosyl on an empty stomach (at least 1 hour before or 2 hours after meals).
Pet Weight | Recommended Dosage |
---|---|
Dogs up to 12 lbs | 1 tablet per day |
Cats up to 12 lbs | 1 tablet per day |
Cats over 12 lbs | 1 tablet twice daily |
Tip: Do not break or crush tablets, as the enteric coating protects SAMe from stomach acid, ensuring maximum absorption.
Active Ingredient:
Inactive Ingredients:
Denosyl is generally well-tolerated, but some pets may experience:
If side effects persist, consult your veterinarian.
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Denosyl is used to support liver function in dogs and cats by boosting glutathione levels, the livers main detoxifier. It also aids in protecting liver cells from damage caused by toxins, medications, and diseases. Additionally, it may improve cognitive function in aging dogs, acting as a neuroprotector to help with memory and mental sharpness.
Denosyl should be given on an empty stomach for optimal absorption. Food may interfere with the bioavailability of SAMe, reducing its effectiveness. It is best administered at least one hour before or two hours after meals to ensure proper digestion and absorption in the small intestine.
Denosyl contains SAMe, which directly increases glutathione levels to protect liver cells, whereas milk thistle contains silymarin, an antioxidant that supports liver function but does not directly produce glutathione. Some veterinarians recommend combining both for enhanced liver protection, depending on your pets condition.
Denosyl is generally safe for long-term use when given under veterinary supervision. Many pets with chronic liver conditions benefit from continuous supplementation. Regular veterinary check-ups are recommended to monitor liver enzyme levels and adjust dosage as needed.
Yes, Denosyl is often recommended for cats with hepatic lipidosis (fatty liver disease) because it helps boost glutathione production, supporting liver detoxification and function. It is most effective when used alongside proper nutritional support and a veterinarian-approved treatment plan.
Denosyl may help dogs with cognitive dysfunction syndrome (CDS) by providing neuroprotective benefits. SAMe has been studied for its role in brain function, potentially improving memory, behavior, and alertness in aging dogs. Results may take 4-6 weeks of consistent use.
Signs that your pet might need Denosyl include loss of appetite, vomiting, lethargy, jaundice (yellowing of skin/eyes), increased thirst, confusion, or disorientation. If your pet is on long-term medications that affect the liver, your veterinarian may recommend Denosyl as a preventative supplement.
No, Denosyl tablets should not be crushed, split, or chewed because they have an enteric coating that protects SAMe from stomach acid. If your pet refuses to take the tablet, consult your veterinarian about alternative administration methods or flavored formulations.
Denosyl and Denamarin both contain SAMe, but Denamarin also includes silybin, an extract from milk thistle that provides additional liver support. Denamarin may be preferred for pets needing extra antioxidant protection, while Denosyl is ideal for pets that require pure SAMe supplementation.
The duration of Denosyl use depends on your pets condition. Some pets need short-term support for temporary liver stress, while others with chronic liver disease or cognitive decline may require lifelong supplementation. Always follow your veterinarians recommendations for the best results.